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MBL Catalyst, Volume 3, Number 1, Spring 2008

Full magazine (PDF format)

Supplemental Material

Do You Know These People?
Help us identify the members of the 1979 Embryology course. Click the thumbnail for a larger image:
If you can identify anyone, please e-mail Diana Kenney: dkenney@mbl.edu.

  • Cover: Participants in the Physiology course (and some of their children) take a break from the laboratory to mix science and fun on a beach in Woods Hole. In the foreground is a sand sculpture they created of the mitotic spindle, the kinetic structure that separates chromosomes during cell division. Photo courtesy of Ron Vale.
  • Inside cover: MBL summer course (T. Kleindinst), Gary Borisy, MBL Director and CEO (D. Cutrona);
  • Table of Contents: (top) Physiology course students and faculty (courtesy of R. Vale), (left upper) SPINES course (T. Kleindinst), (left center) Researchers setting out to make gas flux measurements of a soybean field in Brazil during the dry season (Gillian Galford), (right center) illustration of Drosophila (Howard Hughes Medical Institute);
  • p. 2-3: (top) Lillie building (P. Oldham), (background) MBL’s collecting boat, RV Gemma (P. Oldham), (left and right) MBL’s squid gate (H. Luther);
  • p. 2: (inset) Karen Mesce (J. Sedgewick), (right) Physiology student (R. Vale), (bottom) Semester in Environmental Science students collecting samples (T. Kleindinst);
  • p. 3: (inset) Eric Wieschaus (R. Vale), MBL courses (T. Kleindinst);
  • p. 4: (top) Laser scanning confocal image of embryonic hippocampal neurons in vitro (L. Collis/BioCurrents Research Center), SPINES course (T. Kleindinst), MBL student (E. Armstrong);
  • p. 5: Kristina Micheva (S.J. Smith), (bottom background) Frontiers in Reproduction course (J. Cherry), (bottom inset) MBL course (T. Kleindinst), (top) MBL 4th of July parade sculpture (K. Wiens);
  • p. 6: Visualization of the meiotic spindle in a rhesus monkey oocyte arrested in Meiosis II, using the Oosight spindle imaging system during enucleation. The spindle is near the top in the 12 o'clock position. The Oosight imaging system was developed by Cambridge Research and Instrumentation, Inc., licensing technology invented at the MBL;
  • p. 7: Sample of a species page found at www.eol.org, Albuquerque crust, (Z. Cardon), sea sponge (D. Remsen);
  • p. 8-9: (background) Researchers setting out to make gas flux measurements of a soybean field in Brazil during the dry season (G. Galford);
  • p. 8: Gillian Galford (courtesy of G. Galford);
  • p. 10: neuron illustration (T. Gunther), (inset) neuronal tumor (J. Hinsch);
  • p. 11: Drosophila (Howard Hughes Medical Institute), Michael Dickinson (W. Korff), Janis Weeks (M.D. Cohen), (bottom) songbird illustration (G. Zlatkis);
  • p. 12: (left) Ron Vale (L. Rubenstein), mitotic spindles in the sand (courtesy of R. Vale), Physiology course student at microscope (courtesy of R. Vale);
  • p. 13: (top) Physiology students and faculty members (courtesy of R. Vale), Physiology course experiment (courtesy of R. Vale);
  • p. 14: Semester in Environmental Science student and faculty Ann Giblin collecting samples in West Falmouth (MA) harbor (T. Kleindinst), tiger (U.S. Fish & Wildlife Service), Frontiers in Reproduction course experiment (J. Cherry);
  • p. 15: Various loaned equipment (H. Luther), Martha Peterson (T. Kleindinst);
  • p. 16: John Dowling (T. Kleindinst);
  • p. 17: MBL Embryology course 1979 (from the MBL Archives);
  • Back cover: Pseudocolor image depicting the binding of recombinant myosin 1c fragments to an isolated bullfrog saccular hair cell (J. Cyr and R. Susa)

Learning to Transform

Science as a Calling

Galford, G.L., J.F. Mustard, J. Melillo, A. Gendrin, C.C. Cerri, and C.E.P. Cerri. 2008. Wavelet analysis of MODIS time series to detect expansion and intensification of row-crop agriculture in Brazil. Remote Sensing of Environment 112, 576-587.

Brown-MBL Graduate Program in Biological and Environmental Science

Brown University Land-Cover and Land-Use Change Research Group

Brown University Environmental Change Initiative

Pathfinder Program in Environmental Sustainability

Wired to Learn

News & Notes

  • Nitrogen Pollution Overwhelms Filtering Capability of Streams:
    Mulholland, Patrick J. et al. Stream denitrification across biomes and its response to anthropogenic nitrate loading. Nature, 13 March 2008, Vol. 452, Issue 7184, 202-205.

  • Microscope System Based on MBL Technology Illuminates Stem Cell Research: Byrne, J.A., D.A. Pedersen, L.L. Clepper, M. Nelson, W.G. Sanger, S. Gokhale, D.P. Wolf, and S.M. Mitalipov (2007). Producing primate embryonic stem cells by somatic cell nuclear transfer. Nature 450: 497-502.

    Shribak, M. and R. Oldenbourg. 2003. Techniques for fast and sensitive measurements of two-dimensional birefringence distributions. Appl. Opt. 42: 3009-17.

    Liu, L., R. Oldenbourg, J.R. Trimarchi, and D.L. Keefe. 2000. A reliable, noninvasive technique for spindle imaging and enucleation of mammalian oocytes. Nature Biotech. 18: 223-225.

    Oldenbourg, R., and Mei, G. 1995. New polarized light microscope with precision universal compensator. J. Microscopy 180: 140-147.

  • The Evolutionary Secrets of Desert Cells:
    Cardon, Z.G., Gray, D.W., and Lewis, L. A. 2008. The green algal underground - evolutionary secrets of desert cells. Bioscience 58 (2): 114-122.

  • Sponge Offers Insights into the Basics of Immunity:
    Sabella, C., E. Faszewski, L. Himic, K.M. Colpitts, J. Kaltenbach, M.M. Burger, and X. Fernàndez-Busquets. 2007. Cyclosporin A suspends transplantation in the marine sponge Microciona prolifera. J. Immunol. 179: 5927-35.

  • MBL Creates Portal for Online "Macroscope" to Explore Life's Mysteries:
    Encyclopedia of Life
    Biodiversity Heritage Library

MBL Moment

Cool Tool
MBL Loaned Equipment Program Participating Vendors

Scientist’s Eye View


Embryology course

Rosenthal, E., T. Hunt, and J.V. Ruderman. 1980. Selective translation of mRNA controls the pattern of protein synthesis during early development of the surf clam, Spisula solidissima. Cell 20: 487-494.

Evans, T., E. Rosenthal, J. Youngblom, D. Distal, and T. Hunt. 1983. A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell 33: 389-396.

Timothy Hunt Nobel Prize Lecture

Murray, A.W. 2004. Recycling the cell cycle: cyclins revisited. Cell 116: 221-234.

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