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MBL Catalyst, Volume 7, Number 2, Fall 2012
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Fall 2012 Supplementary Materials
Click here for photo captions and links for the Fall 2012 issue of Catalyst.

Pp. 2-3: Introduction

Connectome Project, Harvard University Center for Brain Science (Jeff Lichtman)

Kandel, E. In Search of Memory (New York: W.W. Norton & Co., 2006).

Seung, S. I Am My Connectome (TED Talk, 2010): http://www.ted.com/talks/sebastian_seung.html

Seung, S. Connectome: How the Brain’s Wiring Makes Us Who We Are. (New York: Houghton Mifflin Harcourt, 2012).

Pp. 4-5: From Molecules to Mind

Centers for Disease Control (2012) Community Report from the Autism and Developmental Disabilities Monitoring (ADDM) Network. Prevalence of Autism Spectrum Disorders Among Multiple Areas of the United States in 2008. http://www.cdc.gov/ncbddd/autism/addm.html

MBL Courses: http://hermes.mbl.edu/education/courses/summer/index.html

Pp. 6-7: News & Notes

Zakon HH (2012) Adaptive evolution of voltage-gated sodium channels: The first 800 million years. PNAS 109: 10619-10625.

First Map of the Bacterial Makeup of Health Humans is Published

Huttenhower C, et al (The Human Microbiome Project Consortium) (2012) Structure, function and diversity of the healthy human microbiome. Nature 486: 207-214.

Methe BA, et al (The Human Microbiome Project Consortium) (2012) A framework for human microbiome research. Nature 486: 215-221

Huse SA, et al (2012) A core human microbiome as viewed through 16S rRNA sequence clusters. PLoS ONE 7(6): e34242. doi:10.1371/journal.pone.0034242 

Turtle Middle Ear is Specialized for Underwater Hearing

Christensen-Dalsgaard J, et al (2012) Specialization for underwater hearing by
the tympanic middle ear of the turtle, Trachemys scripta elegans. Proc. R. Soc. B

Vale, Sheetz, and Spudich Receive Lasker Award for Basic Medical Research

MBL Press Release

Sheetz MP and Spudich JA (1983) Movement of myosin-coated fluorescent beads on actin cables in vitro. Nature 303, 31-35.

Spudich JA, Kron SJ and Sheetz MP (1985) Movement of myosin-coated beads on oriented filaments reconstituted from purified actin. Nature 315, 584-586.

Vale RD, Schnapp BJ, Reese TS, and Sheetz MP (1985) Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon. Cell 40, 559-569.

Vale RD, Reese TS, and Sheetz MP (1985) Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell 42, 39-50.

Vale RD, Schnapp BJ, Mitchison T, Steuer E, Reese TS, and Sheetz MP (1985) Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro. Cell 43, 623-632.

Vale RD (2012) How lucky can one be? A perspective from a young scientist at the right place at the right time. Nature Medicine 18: 1-3.

Clapp, P. (Winter 1986) Trucking Down The Axon. MBL Science

Salmon ED (1995) VE-DIC light microscopy and the discovery of kinesin. Trends Cell Biol. 5: 154-8.

Pp. 8-9: Opening the Senses

MBL Program in Sensory Physiology and Behavior

Wardill TJ, Gonzalez-Bellido PT, Crook RJ, and Hanlon RT (2012) Neural control of tuneable skin iridiscence in squid. Proc. Roy. Soc. B, doi: 10.1098/rspb.2012.1374

Insane in the chromatophores (Video, 2012). Backyard Brains. http://www.backyardbrains.com/home.aspx or http://www.youtube.com/watch?v=G-OVrI9x8Zs

Pp. 10-11: A Revolution Born in Nature

Center for Functional Connectomics (George Augustine)

Arenkeil BR et al (2007) In vivo light-induced activation of neural circuitry in transgenic mice expressing Channelrhodopsin-2. Neuron 54, 205–218.

Boyden ES (2011) A history of optogenetics: The development of tools for controlling brain circuits with light. F1000 Reports Biology 3:11.

Boyden ES et al (2005) Millisecond-timescale, genetically targeted optical control of neural activity. Nature Neuro. 8: 1263-1268

Chow BY et al (2010) High-performance genetically targetable optical neural silencing by light-driven proton pumps. Nature 463: 98-102.

Deisseroth K. Optogenetics: Controlling the brain with light. Scientific American, October 20, 2010.

Fenno L, Yizhar O, and Deisseroth K (2011) The development and application of optogenetics. Ann. Rev. Neurosci. 34: 389-412.

Fortin DL et al (2011) Optogenetic photochemical control of designer K+ channels in mammalian neurons. J. Neurophys. 106: 488-96.

Mancuso JJ et al (2010) Optogenetic probing of functional brain circuitry. Exp. Physiol. 96: 26-33.

Nagel G et al (2003) Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. PNAS 100: 13940-13945.

 Optogenetics: Controlling the brain with light (Video, 2011). McGovern Institute For Brain Research, MIT.

Peron S and Svoboda K (2011) From cudgel to scalpel: Toward precise neural control with optogenetics. Nature Methods 8: 30-34.

Scanziani M and Hausser M (2009) Electrophysiology in the age of light. Nature 461: 930-939.

Stoeckenius W (1999) Bacterial rhodopsins: Evolution of a mechanistic model for the ion pumps. Protein Science 8: 447-459.

Stoeckenius W and Oesterhelt D (1973) Functions of a new photoreceptor membrane. PNAS 70: 2853-2857.

Wang H et al. (2007) High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice. PNAS 104: 8143-8148.

Zhao S et al (2011) Cell-type specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function. Nat Methods 8: 745–752.

Page 12-13: Cracking the Brain's Code

MBL Methods in Computational Neuroscience Course

Allen Institute for Brain Science

Christof Koch lab, California Institute of Technology

Bhattacharjee Y (2012) A vision of how mouse vision can reveal consciousness’ secrets. Science 335: 1426-1427.

Crick F and Koch C (1990) Towards a neurobiological theory of consciousness.
Semin Neurosci 2:263–275

Crick F and Koch C (2003) A framework for consciousness.  Nature Neurosci 6: 119-126.

Koch C. Consciousness: Confessions of a Romantic Reductionist (Cambridge, Mass: The MIT Press, 2012).

Koch C and Reid RC (2012) Neuroscience: Observatories of the mind. Nature 483: 397.

P. 15: Cool Tool: The Ultimate Voltage Sensor

Cohen LB et al (1968) Light scattering and birefringence changes during nerve activity. Nature 218: 438-441.

Jin L et al (2012) Single action potentials and subthreshold electrical events imaged in neurons with a fluorescent voltage probe. Neuron 75: 779-785.

Kralj JM et al (2011) Optical recording of action potentials in mammalian neurons using a microbial rhodopsin. Nature Methods 9: 90-95.

Peterka DS, Takahashi H and Yuste R (2011) Imaging voltage in neurons. Neuron 69: 9-21.

Salzberg BM, Davila HV and Cohen LB (1973) Optical recording of impulses in individual neurones of an invertebrate central nervous system. Nature 246: 508-509.

P. 16: What We Need to Learn

Simons Foundation Autism Research Initiative

  P. 17: Memorabilia: Squid Central

Armstrong, CM. Sodium and potassium channels and propagation of the nerve impulse: A tribute to Cole and Hodgkin. In Barlow RB, Dowling JE and Weissmann G, eds. The Biological Century: Friday Evening Talks at the Marine Biological Laboratory. (Woods Hole, Mass.: The Marine Biological Laboratory, 1993), pp. 155-172.

Squire LR. The History of Neuroscience in Autobiography, Vol. 1 (Washington, DC: The Society for Neuroscience, 1996), pp. 554-586 (John Z. Young).

Williams LW. The Anatomy of the Common Squid, Loligo pealii, Lesueur. (Leiden, Holland: E.J. Brill, 1910).