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The Kensal E. van Holde Lectureship in Physiology
7/20/10 - 4:00 PM, Lillie Auditorium
"Mechanics and Dynamics of Cell Shapes"
Julie Theriot, Stanford University
Dr. Julie Theriot is an Associate Professor of Biochemistry as well as Microbiology & Immunology at Stanford University. Dr. Theriot received a B.S. in Biology and Physics in 1988 from the Massachusetts Institute of Technology and a Ph.D. in Cell Biology in 1993 from the University of California, San Francisco.
Her interests are the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Dr. Theriot's studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis.
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Kensal E. van Holde received both B.S. and Ph.D. degrees from the University of Wisconsin. Trained as a physical chemist, his early interests lay in the synthetic polymer field, which led to initial employment in industry. Dr. van Holde returned to academia in 1957, as an assistant professor at the University of Illinois. There he met J. Woodland Hastings, who asked him to join the faculty of the MBL Physiology course in 1962. He served as a course faculty member for five years, and later as course director from 1977 to 1981.
His experiences in the Physiology course marked a turning point in Dr. van Holde’s career. The enthusiasm of the staff and students at the MBL fired an excitement for biological research that dominated all of his subsequent work. Indeed, the two major themes of his career—the structure and function of oxygen transport proteins, and the fine structure of chromatin—both had their seeds in work conducted at the MBL.
This fascination with the MBL and a love for Woods Hole has led the van Holde family to return nearly every summer for more than 40 years. During that time Dr. van Holde has served on both the Board of Trustees and Executive Committee of the MBL. He is also a member of the American Academy of Arts and Sciences and the National Academy of Sciences.
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