| Tuesday, August 9 |
| 9:00 - 9:10 |
Introductions |
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| 9:10 - 9:45 |
Utz Herbig, Ph.D.
UMDNJ
Telomere Dysfunction-Induced Senescence in Aging and Cancer |
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| 9:45 - 10:10 |
Emmanuel Skordalakes Ph.D.
Wistar Institute
Telomerase Structure Function |
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| 10:20 - 10:50 |
Break |
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| 10:50 -11:25 |
Jan van Deursen, Ph.D.
Mayo Clinic College of Medicine
Inhibition of APC/CCdc20 by BubR1 regulates health- and life span |
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| 11:25 - 12:00 |
Avram Hershko, M.D., Ph.D.
Marine Biological Laboratory
Regulation of the APC/C ubiquitin ligase in the cell cycle: possible implications in aging |
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| 12:00 - 1:15 |
Lunch |
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| 1:15 - 1:50 |
Marion Schmidt, Ph.D.
Albert Einstein College of Medicine
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae |
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| 1:50 - 2:25 |
Stephen Young, M.D.
University of California at Los Angeles
Fresh Insights into Nuclear Lamins and Laminopathies from Genetically Modified Mice |
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| 2:25 - 3:00 |
John Sedivy, Ph.D.
Brown University
The involvement of the c-Myc proto-oncogene in aging |
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| Wednesday, August 10 |
| 9:00 – 9:35 |
Wei Gu, Ph.D.
Columbia University
p53 acetylation in tumor suppression and aging |
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| 9:35 - 10:10 |
Andrew Wurmser, Ph.D.
University of California at Berkeley
Glioma Cells Contribute to the Formation of Tumor Blood Capillaries |
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| 10:10 - 10:40 |
Break |
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| 10:40 - 11:15 |
Rochelle Buffenstein, Ph.D.
University of Texas Health Science Center, San Antonio
Cancer Resistance and Genomic Stability in the Extraordinarily Long-Lived Naked Mole-Rat |
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| 11:15 - 11:50 |
Alex Brodsky, Ph.D.
Brown University
Mechanisms from Genomics during Drosophila Aging |
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| 11:50 - 12:25 |
Anthony De Tomaso, Ph.D.
University of California at Santa Barbara
Aging and Regeneration in the Basal Chordate Botryllus schlosseri |
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| 12:30 - 1:45 |
Lunch |
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| 1:45 - 2:20 |
Sean Morrison, M.D.
University of Michigan
Maintenance of neurological function and adult stem cells by Bmi-1 |
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| 2:20 - 2:55 |
Ronald Davis, Ph.D.
Scripps Research Institute
Age-dependent memory impairments analyzed by functional cellular imaging |
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| 2:55 - 3:30 |
Benjamin Eaton, Ph.D.
University of Texas Health Science Center, San Antonio
Increased presynaptic function by dietary restriction improves motor performance in a motor disease model |
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| Thursday, August 11 |
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| 9:00 - 9:35 |
Wulf Palinski, M.D.
University of California at San Diego
Targeting age-related diseases and aging mechanisms by interfering with maternal immunity and in utero programming |
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| 9:35 - 10:10 |
David Harrison, Ph.D.
The Jackson Laboratory
Testing the Hypothesis that Regulation of Female Reproductive Senescence is Cell Autonomous |
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| 10:10 - 10:40 |
Break |
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| 10:40 - 11:15 |
C. Ronald Kahn, M.D.
Joslin Diabetes Center, Harvard Medical School
Role of Adipose Tissue and miRNAs in Cell Non-Autonomous Regulation of Longevity and Stress Resistance Across an Evolutionary Spectrum |
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| 11:15 - 11:50 |
Adam Antebi, Ph.D.
Baylor College of Medicine
Nuclear hormone receptor control of the life plan and life span |
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| 11:50 - 12:25 |
Heidi Tissenbaum, Ph.D.
A. J. Marian Walhout, Ph.D.
University of Massachusetts Medical School
Dissecting C. elegans insulins using a systems approach |
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| 12:30 - 1:45 |
Lunch |
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| 1:45 - 2:20 |
James Collins, Ph.D.
Boston University
A Network Biology Approach to Aging: Integrating Synthetic Biology and Systems Biology |
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| 2:20 - 2:55 |
Anthony Sauve, Ph.D.
Weill Medical College of Cornell University
Nicotinamide riboside is an endogenous neuroprotective agent that protects against mitochondrial dysfunction and genotoxic stress |
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| 2:55 - 3:30 |
David Sinclair, Ph.D.
Harvard Medical School
Insights into the importance of mitochondrial function in aging |
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4th Annual Joshua Lederberg Lecture
8:00 pm Lillie Auditorium
Introduction by
George Martin, M.D.
Speaker
Gerald Weissmann, M.D.
New York University School of Medicine
"The Biochemistry of Inflammation: from Microciona to the Microbiome"
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