| Monday, August 3 |
| 8:15 - 8:30 |
Introductions |
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|
| 8:30 - 9:15 |
Ao-Lin Hsu, Ph.D.
University of Michigan
The Role of Heat-Shock Factor in the Regulation of Longevity |
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|
| 9:15 - 10:00 |
Pankaj Kapahi, Ph.D.
Buck Institute for Age Research
The Conserved Role of the TOR Pathway in Mediating Lifespan extension by DR |
|
|
| 10:00 - 10:30 |
Break |
|
|
| 10:30 - 11:15 |
Lawrence A. Donehower, Ph.D.
Baylor College of Medicine
Extension of Longevity in p53 Mutant Mice |
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|
| 11:15 - 12:00 |
Makoto Kuro-o, M.D., Ph.D.
University of Texas Southwestern Medical Center at Dallas
The Anti-Aging Mechanism Mediated by Klotho |
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|
| 12:00 - 1:00 |
Lunch |
|
|
| 1:00 - 1:45 |
S. Michal Jazwinski, Ph.D.
Tulane University Health Sciences Center
Aging in Natural Yeast Populations |
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|
| 1:45 - 2:30 |
Hartmut Geiger, Ph.D.
University of Cincinnati
Genomic Integrity and DNA-Repair Pathways in Aging Hematopoietic Stem Cells |
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|
| 2:30 - 3:15 |
D. Leanne Jones, Ph.D.
The Salk Institute for Biological Studies
Control of Germline Stem Cell Behavior During Aging |
|
|
| 3:15 - 4:00 |
Norman Arnheim, Ph.D.
University of Southern California
Molecular Studies of the Paternal Age Effect |
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|
| Tuesday, August 4 |
| 8:00 - 8:45 |
Irina M. Conboy, Ph.D.
University of California at Berkeley
Understanding the Molecular Mechanisms of Stem Cell Aging |
|
|
| 8:45 - 9:30 |
Erik Lee Snapp, Ph.D.
Albert Einstein College of Medicine
Age-related Oxidative Damage and the ER Folding Environment |
|
|
| 9:30 - 10:15 |
Alexei Tulin, Ph.D.
Fox Chase Cancer Center
Poly(ADP-ribosyl)ating enzymes in aging control |
|
|
| 10:15 - 10:45 |
Break |
|
|
| 10:45 - 11:30 |
Josephine Hoh, Ph.D.
Yale University
Insights into Genetics of Age-Related Macular Degeneration |
|
|
| 11:30 - 12:15 |
Siu Sylvia Lee, Ph.D.
Cornell University
Systematic Analysis of Genetic Determinants in C.elegans |
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|
| 12:15 - 1:15 |
Lunch |
|
|
| 1:15 - 2:00 |
Norman Sharpless, M.D.
The University of North Carolina
Ink4a/Arf Expression in Aging |
|
|
| 2:00 - 2:45 |
William G. Dunphy, Ph.D.
California Institute of Technology
Checkpoint Mediator Proteins as Both Negative and Positive Regulators of Cellular Senescence |
|
|
| 8:00 |
2nd Annual Joshua Lederberg Lecture
8:00 PM, Lillie Auditorium
Introduction by
Gerald Weissmann, M.D.
Speaker
David Baltimore, Ph.D.
California Institute of Technology
"MicroRNAs as Players in Immune and Inflammatory Responses"
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|
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| Wednesday, August 5 |
|
|
| 8:00 - 8:45 |
Laura J. Niedernhofer, M.D., Ph.D.
University of Pittsburgh
The Role of DNA Repair in Attenuating Aging |
|
|
| 8:45 - 9:30 |
Judd M. Aiken, Ph.D.
University of Wisconsin-Madison
Mitochondrial DNA Abnormalities: Impact on Sarcopenia |
|
|
| 9:30 - 10:15 |
Robert Alan Reenan, Ph.D.
BRown University
Genetic Recoding by RNA Editing and the Aging Process |
|
|
| 10:15 - 10:45 |
Break |
|
|
| 10:45 - 11:30 |
S. Kerry Kornfeld, M.D., Ph.D.
Washington University School of Medicine
The Anticonvulsant Ethosuximide Disrupts Sensory Function to Extend C.elegans Lifespan |
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|
| 11:30 - 12:15 |
Charles V. Mobbs, Ph.D.
Mount Sinai School of Medicine
CBP and SATB-1 expression predict, and mediate effects of dietary restriction on, lifespan |
|
|
| 12:15 - 1:15 |
Lunch |
|
|
| 1:15 - 2:00 |
John E. Repine, M.D.
University of Colorado Health Science Center
Oxygen Tolerance, the Metabolic Syndrome, Longevity and Mitochondrial Function |
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|
| 2:00 - 2:45 |
Bruce A. Yankner, M.D., Ph.D.
Harvard Medical School
Micro RNAs and the Regulation of Brain Aging |
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|
| 2:45 - 3:30 |
Stephen F. Heinemann, Ph.D.
Salk Institute for Biological Studies
Alzheimer’s Disease: New Approaches to Therapy |
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